Author(s)
Keywords
Chromosomes, Human, Pair 14, Chromosomes, Human, Pair 17, Leukemia, Promyelocytic, Acute/genetics, Translocation, Genetic, Tretinoin/therapeutic use
Abstract
We present a case of acute promyelocytic leukemia (APL) carrying an atypical translocation involving chromosomes 14 and 17. This translocation could be considered a variant of the APL-specific t(15;17). Positive response to retinoic acid treatment suggests molecular rearrangement of retinoic acid receptor alpha.
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