Changes in ambient temperature or chip temperature result in variations in the in-phase and quadrature (I/Q) gain and phase imbalance. As a consequence, the overall system performance can be seriously degraded, especially in wideband multi-Gb/s systems, where the I/Q imbalance is highly selective in frequency. Unless appropriately considered, temperature drifts can decrease the image rejection ratio (IRR) of the transmitter. This article presents a novel compensation method for temperature-dependent transmitter I/Q imbalance over the entire temperature range. It consists of a simple predistortion technique that, based on a few factory characterizations of gain and phase imbalance, is able to estimate and correct the I/Q imbalance at any temperature, without interrupting the normal functionality of the system. The proposed method is assessed in a 2-GHz, 64-QAM transceiver implemented with real hardware. The measurements show that the proposed approach is able to keep the IRR greater than 35 dB in the entire bandwidth and an error vector magnitude (EVM) lower than 3 over a temperature range of 70 C.