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dc.creatorGuridi-Legarra, J. (Jorge)-
dc.creatorAldave, G. (Guillermo)-
dc.identifier.citationGuridi J, Aldave G. Dianas quirúrgicas en el tratamiento de enfermedades psiquiátricas. Desde el movimiento a las emociones. Neurocirugia (Astur) 2011 Feb;22(1):5-22.es_ES
dc.description.abstractDeep brain stimulation (DBS) for psychiatric disorders refractory to conventional treatments are currently been performed based in the knowledgment obtained in the motor disorder surgery and mainly in Parkinson´s disease. Depression, obsessive-compulsive disorder (OCD) and Tourette syndrome, all of them are cortico-striato-thalamo-cortical pathological process involved in the limbic loop of the basal ganglia. This review describes the different targets in these pathological neuro-psychiatric disorders. For OCD there are currently two targets, ventral striatum (VS) Accumbens nucleus (Nacc) and the subthalamic nucleus (STN). In refractory depression the subgenual area (25 Brodmann area) and VS/Nacc. For Tourette syndrome the ventralis oralis internus and centromedianum/ parafascicularis of the thalamus (Voi and CM/Pf) and the internal part of the globus pallidus (GPi). Currently there are no specific surgical target for each pathological disorder because clinical results reported are very similar after stimulation surgery. In other point, a selected surgical target also may improve different pathologies.es_ES
dc.publisherSociedad Española de Neurocirugíaes_ES
dc.subjectDeep brain stimulationes_ES
dc.subjectParkinson´s diseasees_ES
dc.subjectObsessive-compulsive disorderes_ES
dc.titleDianas quirúrgicas en el tratamiento de enfermedades psiquiátricas. Desde el movimiento a las emocioneses_ES
dc.title.alternativeSurgical targets in Psychiatric disorders. From movement to emotionses_ES

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