Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.creator | Monge, A. (Antonio) | - |
| dc.creator | Aldana, I. (Ignacio) | - |
| dc.creator | Pérez-Silanes, S. (Silvia) | - |
| dc.creator | Torres, E. (Enrique) | - |
| dc.creator | Burguete, A. (Asunción) | - |
| dc.creator | Raquel | - |
| dc.creator | Solano, B. (Beatriz) | - |
| dc.creator | Moreno-de-Viguri, E. (Elsa) | - |
| dc.creator | Ancizu, S. (Saioa) | - |
| dc.date.accessioned | 2014-04-12T17:18:17Z | - |
| dc.date.available | 2014-04-12T17:18:17Z | - |
| dc.date.issued | 2010-02-20 | - |
| dc.identifier.citation | Ancizu S, Moreno E, Solano B, Villar R, Burguete A, Torres E, et al. New 3-methylquinoxaline-2-carboxamide 1,4-di-N-oxide derivatives as anti-Mycobacterium tuberculosis agents. Bioorg Med Chem 2010 4/1;18(7):2713-2719 | es_ES |
| dc.identifier.issn | 0968-0896 | - |
| dc.identifier.uri | https://hdl.handle.net/10171/35790 | - |
| dc.description.abstract | Mycobacterium tuberculosis (M.Tb) is a bacillus capable of causing a chronic and fatal condition in humans known as tuberculosis (TB). It is estimated that there are 8 million new cases of TB per year and 3.1 million infected people die annually. Thirty-six new amide quinoxaline 1,4-di-N-oxide derivatives have been synthesized and evaluated as potential anti-tubercular agents,obtaining biological values similar to the reference compound, Rifampin (RIF). | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | Elsevier | es_ES |
| dc.relation | RIDIMEDCHAG-CYTED and PIUNA project from University of Navarra. We also wish to express our gratitude to the Tuberculosis Antimicrobial Acquisition & Coordinating Facility (TAACF) for the evaluation of the anti-tuberculosis activity through research and development contracts. S.A. | - |
| dc.rights | info:eu-repo/semantics/openAccess | es_ES |
| dc.subject | Rifampin | es_ES |
| dc.subject | Mycobacterium tuberculosis | es_ES |
| dc.subject | Quinoxaline 1,4-di-N-oxide | es_ES |
| dc.subject | Anti-tuberculosis agents | es_ES |
| dc.title | New 3-methylquinoxaline-2-carboxamide 1,4-di-N-oxide derivatives as anti- Mycobacterium tuberculosis agents. | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.identifier.doi | http://dx.doi.org/10.1016/j.bmc.2010.02.024 | es_ES |
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