Full metadata record
DC Field | Value | Language |
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dc.creator | Conesa, C.M. (Carlos M.) | - |
dc.creator | Saez, Á. (Ángela) | - |
dc.creator | Navarro-Neila, S. (Sara) | - |
dc.creator | Lorenzo, L. (Laura) de | - |
dc.creator | Hunt, A.G. (Arthur G.) | - |
dc.creator | Sepúlveda, E.B. (Edgar B.) | - |
dc.creator | Baigorri, R. (Roberto) | - |
dc.creator | García-Mina, J.M. (José María) | - |
dc.creator | Zamarreño, A.M. (Angel Maria) | - |
dc.creator | Sacristán, S. (Soledad) | - |
dc.creator | Pozo, J.C. (Juan C.) del | - |
dc.date.accessioned | 2020-04-28T09:46:16Z | - |
dc.date.available | 2020-04-28T09:46:16Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Conesa, C.M. (Carlos M.); Saez, Á. (Ángela); Navarro-Neila, S. (Sara); et al. "Alternative polyadenylation and salicylic acid modulate root responses to low nitrogen availability". Plants. 9 (2), 2020, 251 | es |
dc.identifier.issn | 2223-7747 | - |
dc.identifier.uri | https://hdl.handle.net/10171/58949 | - |
dc.description.abstract | Nitrogen (N) is probably the most important macronutrient and its scarcity limits plant growth, development and fitness. N starvation response has been largely studied by transcriptomic analyses, but little is known about the role of alternative polyadenylation (APA) in such response. In this work, we show that N starvation modifies poly(A) usage in a large number of transcripts, some of them mediated by FIP1, a component of the polyadenylation machinery. Interestingly, the number of mRNAs isoforms with poly(A) tags located in protein-coding regions or 5 '-UTRs significantly increases in response to N starvation. The set of genes affected by APA in response to N deficiency is enriched in N-metabolism, oxidation-reduction processes, response to stresses, and hormone responses, among others. A hormone profile analysis shows that the levels of salicylic acid (SA), a phytohormone that reduces nitrate accumulation and root growth, increase significantly upon N starvation. Meta-analyses of APA-affected and fip1-2-deregulated genes indicate a connection between the nitrogen starvation response and salicylic acid (SA) signaling. Genetic analyses show that SA may be important for preventing the overgrowth of the root system in low N environments. This work provides new insights on how plants interconnect different pathways, such as defense-related hormonal signaling and the regulation of genomic information by APA, to fine-tune the response to low N availability. | - |
dc.language.iso | en | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | Root development | - |
dc.subject | Alternative polyadenylation | - |
dc.subject | Nitrogen starvation | - |
dc.subject | Salicylic acid | - |
dc.title | Alternative polyadenylation and salicylic acid modulate root responses to low nitrogen availability | - |
dc.type | info:eu-repo/semantics/article | - |
dc.identifier.doi | 10.3390/plants9020251 | - |
dadun.citation.number | 2 | - |
dadun.citation.publicationName | Plants | - |
dadun.citation.startingPage | 251 | - |
dadun.citation.volume | 9 | - |
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