Full metadata record
DC Field | Value | Language |
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dc.creator | Pippa, R. (Raffaella) | - |
dc.creator | Odero, M.D. (Maria Dolores) | - |
dc.date.accessioned | 2020-06-10T12:15:58Z | - |
dc.date.available | 2020-06-10T12:15:58Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Pippa, R. (Raffaella); Odero, M.D. (Maria Dolores). "The role of MYC and PP2A in the initiation and progression of myeloid leukemias". Cells. 9 (3), 2020, 544 | es |
dc.identifier.issn | 2073-4409 | - |
dc.identifier.uri | https://hdl.handle.net/10171/59035 | - |
dc.description.abstract | The MYC transcription factor is one of the best characterized PP2A substrates. Deregulation of the MYC oncogene, along with inactivation of PP2A, are two frequent events in cancer. Both proteins are essential regulators of cell proliferation, apoptosis, and differentiation, and they, directly and indirectly, regulate each other's activity. Studies in cancer suggest that targeting the MYC/PP2A network is an achievable strategy for the clinic. Here, we focus on and discuss the role of MYC and PP2A in myeloid leukemias. | - |
dc.description.sponsorship | This work was supported by grants from the ISCIII and Spanish Ministry of Economy and Competiveness (PI17/02272) and by CIBERONC (CB16/12/00489) (Co-financed with FEDER funds), Departamento de Salud of the Government of Navarra (29/2015) and Departamento de Desarrollo Económico of the Government of Navarra (PI020 PDX-AML) (M.D.O.) and from the Prostate Cancer Foundation (R.P.). | - |
dc.language.iso | en | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | PP2A | - |
dc.subject | MYC | - |
dc.subject | Myeloid leukemia | - |
dc.subject | AML | - |
dc.subject | CML | - |
dc.title | The role of MYC and PP2A in the initiation and progression of myeloid leukemias | - |
dc.type | info:eu-repo/semantics/review | - |
dc.description.note | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license | - |
dc.identifier.doi | 10.3390/cells9030544 | - |
dadun.citation.number | 3 | - |
dadun.citation.publicationName | Cells | - |
dadun.citation.startingPage | 544 | - |
dadun.citation.volume | 9 | - |
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