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dc.creatorFederico, C. (Cinzia)-
dc.creatorSacco, A. (Antonio)-
dc.creatorBelotti, A. (Angelo)-
dc.creatorRibolla, R. (Rossella)-
dc.creatorCancelli, V. (Valeria)-
dc.creatorGiacomini, A. (Arianna)-
dc.creatorRonca, R. (Roberto)-
dc.creatorChiarini, M. (Marco)-
dc.creatorImberti, L. (Luisa)-
dc.creatorMarini, M. (Mirella)-
dc.creatorRossi, G. (Giuseppe)-
dc.creatorPresta, M. (Marco)-
dc.creatorPaiva, B. (Bruno)-
dc.creatorRoccaro, A.M. (Aldo M.)-
dc.date.accessioned2021-11-02T08:20:07Z-
dc.date.available2021-11-02T08:20:07Z-
dc.date.issued2019-
dc.identifier.citationFederico, C. (Cinzia); Sacco, A. (Antonio); Belotti, A. (Angelo); et al. "Circulating microRNAs and their role in multiple myeloma". Non-Coding RNA. 5 (2), 2019, 37es_ES
dc.identifier.issn2311-553X-
dc.identifier.urihttps://hdl.handle.net/10171/62297-
dc.description.abstractMultiple myeloma (MM) is a plasma cell dyscrasia characterized by bone marrow infiltration of clonal plasma cells. The recent literature has clearly demonstrated clonal heterogeneity in terms of both the genomic and transcriptomic signature of the tumor. Of note, novel studies have also highlighted the importance of the functional cross-talk between the tumor clone and the surrounding bone marrow milieu, as a relevant player of MM pathogenesis. These findings have certainly enhanced our understanding of the underlying mechanisms supporting MM pathogenesis and disease progression. Within the specific field of small non-coding RNA-research, recent studies have provided evidence for considering microRNAs as a crucial regulator of MM biology and, in this context, circulating microRNAs have been shown to potentially contribute to prognostic stratification of MM patients. The present review will summarize the most recent studies within the specific topic of microRNAs and circulating microRNAs in MM.es_ES
dc.description.sponsorshipAMR: Associazione Italiana per la Ricerca sul Cancro (AIRC); European Hematology Association (EHA); Fondazione Regionale per la Ricerca Biomedica (Regione Lombardia) ERA-NET TRANSCAN-2 065 JTC 2016; RR: AMR: Associazione Italiana per la Ricerca sul Cancro (AIRC); MP: IG AIRC grant n◦ 18493; AG: Fondazione Cariplo (2016-0570).es_ES
dc.language.isoenges_ES
dc.publisherMDPI AGes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectMultiple myelomaes_ES
dc.subjectPlasma Cell dyscrasiaes_ES
dc.subjectmiRNAses_ES
dc.subjectCirculating miRNAses_ES
dc.subjectCirculating exosomal-miRNAses_ES
dc.titleCirculating microRNAs and their role in multiple myelomaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.description.noteThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.es_ES
dc.identifier.doi10.3390/ncrna5020037-
dadun.citation.number2es_ES
dadun.citation.publicationNameNon-Coding RNAes_ES
dadun.citation.startingPage37es_ES
dadun.citation.volume5es_ES

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