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Perdomo, C.M. (Carolina M.); Frühbeck, G. (Gema); Escalada, J. (Javier). "Impact of nutritional changes on nonalcoholic fatty liver disease". Nutrients. 11 (3), 2019, 677
Non-alcoholic fatty liver disease (NAFLD) is a major global health threat due to its growing
incidence and prevalence. It is becoming the leading cause of liver disease in addition to its strong
association with cardio-metabolic disease. Therefore, its prevention and treatment are of strong public
interest. Therapeutic approaches emphasize lifestyle modifications including physical activity and
the adoption of healthy eating habits that intend to mainly control body weight and cardio-metabolic
risk factors associated with the metabolic syndrome. Lifestyle interventions may be reinforced by
pharmacological treatment in advanced stages, though there is still no registered drug for the specific
treatment of NAFLD. The purpose of this review is to assess the evidence available regarding the
impact of dietary recommendations against NAFLD, highlighting the effect of macronutrient diet
composition and dietary patterns in the management of NAFLD.