Full metadata record
DC FieldValueLanguage
dc.creatorRuiz-Medrano, J. (Jorge)-
dc.creatorMontero, J.A. (Javier A.)-
dc.creatorFlores-Moreno, I. (Ignacio)-
dc.creatorArias, L. (Luis)-
dc.creatorGarcia-Layana, A. (Alfredo)-
dc.creatorRuiz-Moreno, J.M. (José María)-
dc.date.accessioned2021-11-11T08:35:24Z-
dc.date.available2021-11-11T08:35:24Z-
dc.date.issued2019-
dc.identifier.citationRuiz-Medrano, J. (Jorge); Montero, J.A. (Javier A.); Flores-Moreno, I. (Ignacio); et al. "Myopic maculopathy: Current status and proposal for a new classification and grading system (ATN)". Progress in Retinal and Eye Research. 69, 2019, 80 - 115es_ES
dc.identifier.issn1350-9462-
dc.identifier.urihttps://hdl.handle.net/10171/62528-
dc.description.abstractMyopia is a highly frequent ocular disorder worldwide and pathologic myopia is the 4th most common cause of irreversible blindness in developed countries. Pathologic myopia is especially common in East Asian countries. Ocular alterations associated with pathologic myopia, especially those involving the macular area—defined as myopic maculopathy—are the leading causes of vision loss in patients with pathologic myopia. High myopia is defined as the presence of a highly negative refractive error (>−6 to −8 diopters) in the context of eye elongation (26–26.5 mm). Although the terms high myopia and pathologic myopia are often used interchangeably, they do not refer to the same eye disease. The two key factors driving the development of pathologic myopia are: 1) elongation of the axial length and 2) posterior staphyloma. The presence of posterior staphyloma, which is the most common finding in patients with pathologic myopia, is the key differentiating factor between high and pathologic myopia. The occurrence of staphyloma will, in most cases, eventually lead to other conditions such as atrophic, traction, or neovascular maculopathy. Posterior staphyloma is for instance, responsible for the differences between a myopic macular hole (MH)—with and without retinal detachment—and idiopathic MH. Posterior staphyloma typically induces retinal layer splitting, leading to foveoschisis in myopic MH, an important differentiating factor between myopic and emmetropic MH. Myopic maculopathy is a highly complex disease and current classification systems do not fully account for the numerous changes that occur in the macula of these patients. Therefore, a more comprehensive classification system is needed, for several important reasons. First, to more precisely define the disease stage to improve follow-up by enabling clinicians to more accurately monitor changes over time, which is essential given the progressive nature of this condition. Second, unification of the currently-available classification systems would establish standardized classification criteria that could be used to compare the findings from international multicentric studies. Finally, a more comprehensive classification system could help to improve our understanding of the genetic origins of this disease, which is clearly relevant given the interchangeable—but erroneous—use of the terms high and pathologic myopia in genetic researches_ES
dc.description.sponsorshipThis study was supported in part by a grant from the Spanish Ministry of Health, Instituto de Salud Carlos III, Red Temática de Investigación Cooperativa en Salud: "“Prevención, detección precoz, y tratamiento de la patología ocular prevalente, degenerativa y crónica” (RD16/0008/0021).es_ES
dc.language.isoenges_ES
dc.publisherElsevier BVes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectPathologic myopiaes_ES
dc.subjectStaphylomaes_ES
dc.subjectMyopic maculopathyes_ES
dc.subjectMyopic traction maculopathyes_ES
dc.subjectMyopic choroidal neovascularizationes_ES
dc.subjectHigh myopiaes_ES
dc.subjectATN classification systemes_ES
dc.subjectMyopic maculopathy classificationes_ES
dc.titleMyopic maculopathy: Current status and proposal for a new classification and grading system (ATN)es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.description.noteThis is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/).es_ES
dc.identifier.doi10.1016/j.preteyeres.2018.10.005-
dadun.citation.endingPage115es_ES
dadun.citation.publicationNameProgress in Retinal and Eye Researches_ES
dadun.citation.startingPage80es_ES
dadun.citation.volume69es_ES

Files in This Item:
Thumbnail
File
1-s2.0-S1350946218300508-main.pdf
Description
Size
14.42 MB
Format
Adobe PDF


Statistics and impact

Items in Dadun are protected by copyright, with all rights reserved, unless otherwise indicated.