Precision nutrition and metabolic syndrome management

Abstract

The journal NUTRIENTS published some time ago a special issue about “Precision Nutrition and Metabolic Syndrome Management”, which included a series of articles about the role of bioactive compounds, amino acids/proteins and fatty acids for personalized nutritional applications [1]. In such volume, the emerging concept of precision nutrition was developed in two specific reviews. These articles explain global personalized nutrition in the management of metabolic syndrome features such as obesity, diabetes, dyslipemia, hypertension and other cardiovascular complications [2], and individualized lipid metabolism targeting in cancer [3]. In particular, they describe the role of nutrigenetics, deep phenotyping, family and personal clinical cues, perinatal nutrition and a wide spectrum of data concerning metabolic personalization through omics technologies (metabolomics, epigenomics, metagenomics, and others), whose possibilities were appraised. Indeed, the conceptual framework understanding precision nutrition is based on assessing the interindividual heterogeneity caused by genetic/epigenetic dissimilarities, the lifestyle and environmental exposome diversity, microbiome variations, and singular behavioral/psychological features [4] with clear implications for public health to harmonize personal and population challenges and applications [5].