Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Ibarz-Barberá, M. (Marta) | - |
dc.creator | Hernández-Verdejo, J.L. (José Luis) | - |
dc.creator | Bragard, J. (Jean) | - |
dc.creator | Burguete-Mas, F.J. (Francisco Javier) | - |
dc.creator | Morales-Fernández, L. (Laura) | - |
dc.creator | Tañá-Rivero, P. (Pedro) | - |
dc.creator | Gómez-de-Liaño, R. (Rosario) | - |
dc.creator | Teus, M.A. (Miguel A.) | - |
dc.date.accessioned | 2022-02-01T12:50:11Z | - |
dc.date.available | 2022-02-01T12:50:11Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Barberá, M. I.; Hernández-Verdejo, J. L.; Bragard-Monier, J. (Jean René); et al. "Evaluation of the ultrastructural and in vitro flow properties of the PRESERFLO MicroShunt". Translational Vision Science & Technology. 10 (13), 2021, 26 | es |
dc.identifier.issn | 2164-2591 | - |
dc.identifier.uri | https://hdl.handle.net/10171/62863 | - |
dc.description.abstract | Purpose: To measure the in vitro flow properties of the PRESERFLO implant for comparison with the theoretical resistance to flow. Methods: The PRESERFLO was designed to control the flow of aqueous humor according to the Hagen-Poiseuille (HP) equation. Scanning electron microscopy (SEM) was performed to analyze the ultrastructure, and flow measurements were carried out using a gravity-flow setup. Results: SEM images of the PRESERFLO showed luminal diameters of 67.73 x 65.95 mu m and 63.66 x 70.54 mu m. The total diameter was 337.2 mu m, and the wall was 154 mu m wide. The theoretical calculation of the resistance to flow (R) for an aqueous humor (AH) viscosity of 0.7185 centipoises (cP) was 1.3 mm Hg/(mu L/min). Hence, assuming a constant AH flow of 2 mu L/min, the pressure differential across the device (AP) was estimated to be 2.6 mm Hg. The gravity-flow experiment allowed us to measure the experimental resistance to flow, which was R-E = 1.301 mm Hg/(mu L/min), in agreement with the theoretical resistance to flow R given by the HP equation. Conclusions: The experimental and theoretical flow testing showed that the pressure drop across this device would not be large enough to avoid hypotony unless the resistance to outflow of the sub-Tenon space was sufficient to control the intraocular pressure in the early postoperative period. Translational Relevance: The fluid properties of glaucoma subconjunctival drainage devices determine their specific bleb-forming capacity and ability to avoid hypotony and therefore their safety and efficacy profile. Translational Relevance: The fluid properties of glaucoma subconjunctival drainage devices determine their specific bleb-forming capacity and ability to avoid hypotony and therefore their safety and efficacy profile. | - |
dc.language.iso | en | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | PRESERFLO | - |
dc.subject | Aqueous flow | - |
dc.subject | Pressure drop | - |
dc.subject | Glaucoma surgery | - |
dc.subject | Hagen-Poiseuille | - |
dc.title | Evaluation of the ultrastructural and in vitro flow properties of the PRESERFLO MicroShunt | - |
dc.type | info:eu-repo/semantics/article | - |
dc.description.note | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License | - |
dc.identifier.doi | 10.1167/tvst.10.13.26 | - |
dadun.citation.number | 13 | - |
dadun.citation.publicationName | Translational Vision Science & Technology | - |
dadun.citation.startingPage | 26 | - |
dadun.citation.volume | 10 | - |
Files in This Item:
Statistics and impact
Items in Dadun are protected by copyright, with all rights reserved, unless otherwise indicated.