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dc.creatorArrondo, G. (Gonzalo)-
dc.creatorSolmi, M. (Marco)-
dc.creatorDragioti, E. (Elena)-
dc.creatorEudave-Ramos, L.H. (Luis Humberto)-
dc.creatorRuiz-Goikoetxea, M. (Maite)-
dc.creatorCiaurriz-Larraz, A. (Amaia)-
dc.creatorMagallon-Recalde, S. (Sara)-
dc.creatorCarvalho, A.F. (André F.)-
dc.creatorCipriani, A. (Andrea)-
dc.creatorFusar-Poli, P. (Paolo)-
dc.creatorLarsson, H. (Henrik)-
dc.creatorCorrell, C. (Christoph)-
dc.creatorCortese, S. (Samuele)-
dc.date.accessioned2022-04-27T12:44:35Z-
dc.date.available2022-04-27T12:44:35Z-
dc.date.issued2022-
dc.identifier.citationArrondo-Ostiz, G. (Gonzalo); Solmi, M.; Dragioti, E.; et al. "Associations between mental and physical conditions in children and adolescents: An umbrella review". Neuroscience and Biobehavioral Reviews. 137, 2022, 104662es
dc.identifier.issn0149-7634-
dc.identifier.urihttps://hdl.handle.net/10171/63429-
dc.description.abstractWe mapped the evidence on the type and strength of associations between a broad range of mental and physical conditions in children and adolescents, by carrying out an umbrella review, i.e., a quantitative synthesis of previous systematic reviews and meta-analyses. We also assessed to which extent the links between mental and physical conditions vary across disorders or, by contrast, are transdiagnostic. Based on a pre-established protocol, we retained 45 systematic reviews/meta-analyses, encompassing around 12.5 million of participants. In analyses limited to the most rigorous estimates, we found evidence for the following associations: ADHD-asthma, ADHD-obesity, and depression-asthma. A transdiagnostic association was confirmed between asthma and anxiety/ASD/depression/bipolar disorder, between obesity and ADHD/ASD/depression, and between dermatitis and ASD/ADHD. We conclude that obesity and allergic conditions are likely to be associated with mental disorders in children and adolescents. Our results can help clinicians explore potential links between mental and physical conditions in children/adolescent and provide a road map for future studies aimed at shading light on the underlying factors.-
dc.description.sponsorshipGA was supported by the Spanish Ministry of Science, Innovation and Universities to facilitate the mobility of researchers to foreign higher education and research centers (Ref. CAS19/00249). MR was supported by the 2019 Senior Grant from the Medical Association of Navarre. SM is supported by the European Social Fund and the Spanish Research Agency (Ram ́on y Cajal-2017-22060). AC is supported by the NIHR Oxford Cognitive Health Clinical Research Facility, by an NIHR Research Professorship (Grant number RP-2017-08-ST2-006), by the NIHR Oxford and Thames Valley Applied Research Collaboration, and by the NIHR Oxford Health Biomedical Research Centre (Grant number BRC-1215-20005).-
dc.language.isoen-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.subjectMental-
dc.subjectPhysical-
dc.subjectTransdiagnostic-
dc.subjectUmbrella review-
dc.subjectMeta-analysis-
dc.titleAssociations between mental and physical conditions in children and adolescents: An umbrella review-
dc.typeinfo:eu-repo/semantics/article-
dc.description.notehis is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).-
dc.identifier.doi10.1016/j.neubiorev.2022.104662-
dadun.citation.publicationNameNeuroscience and Biobehavioral Reviews-
dadun.citation.startingPage104662-
dadun.citation.volume137-

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