Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Cortese, S. (Samuele) | - |
dc.creator | Gabellone, A. (Alessandra) | - |
dc.creator | Marzulli, L. (Lucia) | - |
dc.creator | Iturmendi-Sabater, I. (Iciar) | - |
dc.creator | Chica-Duarte, D. (Diego) de la | - |
dc.creator | Piqué, I.M. (Isabella M.) | - |
dc.creator | Solmi, M. (Marco) | - |
dc.creator | Shin, J.I. (Jae Il) | - |
dc.creator | Margari, L. (Lucia) | - |
dc.creator | Arrondo, G. (Gonzalo) | - |
dc.date.accessioned | 2022-05-04T11:22:47Z | - |
dc.date.available | 2022-05-04T11:22:47Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Cortese S, Gabellone A, Marzulli L, Iturmendi-Sabater I, de La Chica-Duarte D, Piqué IM, Solmi M, Shin JI, Margari L, Arrondo G. Association between autism spectrum disorder and diabetes: systematic review and meta-analysis. Neurosci Biobehav Rev. 2022 May;136:104592. | es_ES |
dc.identifier.issn | 0149-7634 | - |
dc.identifier.uri | https://hdl.handle.net/10171/63435 | - |
dc.description.abstract | There is mixed evidence on the link between autism spectrum disorder (ASD) and diabetes. We conducted the first systematic review/meta-analysis on their association. Based on a pre-registered protocol (PROSPERO: CRD42021261114), we searched Pubmed, Ovid, and Web of Science databases up to 6 December 2021, with no language/type of document restrictions. We assessed study quality using the Newcastle-Ottawa Scale (NOS). We included 24 studies (total: 3427,773 individuals; 237,529 with ASD and 92,832 with diabetes) in the systematic review and 20 in the meta-analysis (mean stars number on the NOS: 5.89/10). There was a significant association, albeit characterized by significant heterogeneity, when pooling unadjusted OR (1.535, 95% CI = 1.109-2.126), which remained significant when restricting the analysis to children and type 2 diabetes, but became non-significant when considering adjusted ORs (OR: 1.528, 95% CI = 0.954-2.448). No significant prospective association was found (n = 2) on diabetes predicting ASD (HR: 1.232, 0.826-11.837). Therefore, the association between ASD and diabetes is likely confounded by demographic and clinical factors that should be systematically investigated in future studies. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Autism | es_ES |
dc.subject | Diabetes | es_ES |
dc.subject | Meta-analysis | es_ES |
dc.title | Association between autism spectrum disorder and diabetes: systematic review and meta-analysis | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.editorial.note | This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/). | es_ES |
dc.identifier.doi | 10.1016/j.neubiorev.2022.104592 | - |
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