Full metadata record
DC Field | Value | Language |
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dc.creator | Fuente-García, C. (Carlota) | - |
dc.creator | Muñoz-Negrete, F.J. (Francisco José) | - |
dc.creator | Dompablo, E. (Elisabet) de | - |
dc.creator | Moreno-Montañes, J. (Javier) | - |
dc.creator | Rebolleda, G. (Gema) | - |
dc.date.accessioned | 2022-12-01T13:46:35Z | - |
dc.date.available | 2022-12-01T13:46:35Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Fuente-García, C.; Muñoz-Negrete, F. J.; de Dompablo, E.; et al. "Changes in ocular surface after withdrawal of anti-glaucoma medications following non-penetrating deep sclerectomy". Indian Journal of Ophthalmology. 70 (5), 2022, 1626 - 1633 | es |
dc.identifier.issn | 0301-4738 | - |
dc.identifier.uri | https://hdl.handle.net/10171/64781 | - |
dc.description.abstract | Purpose: To analyze the ocular surface changes in eyes after the withdrawal of anti-glaucomatous drugs when non-penetrating deep sclerectomy (NPDS) is performed. Methods: Thirty-one patients (33 eyes) diagnosed with glaucoma that underwent NPDS were included in this prospective study. The control group included 33 eyes. Four variables were studied using Keratograph 5M (K5M): ocular hyperemia (OH), non-invasive tear film break-up time (NI-BUT), lower tear meniscus height (LTMH), and meibography. LTMH was also measured using the anterior segment module of a Spectralis Fourier-domain optical coherence tomography (FD-OCT) instrument. Moreover, an evaluation of corneal and conjunctival staining was performed. In the glaucoma group, five visits were carried out: pre-surgery, 1 week after surgery, and 1 month, 3 months, and 6 months after surgery. In control groups, examinations were performed in only one visit. In addition, patients were asked to answer two questionnaires: Ocular Surface Disease Index (OSDI) and National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) before and 6 months after surgery. Results: Before NPDS, eyes showed worse objective data than healthy control subjects (P <= 0.049). In this group, a significant improvement was observed in questionnaire responses (P < 0.001), LTMH-FD-OCT (P = 0.037), LTMH-K5M (P = 0.025), K5M-OH (P = 0.003), NI-BUT (P = 0.022), and conjunctival and corneal staining (P < 0.001). No significant differences were observed between groups in FD-OCT and K5M LTMH, NI-BUT, corneal-conjunctival staining, nor in the most OH sector values at 6 months (P & GE; 0.62). Conclusion: A significant improvement in the ocular surface was observed 6 months after NPDS, suggesting that the withdrawal of the topical anti-glaucomatous treatment had a beneficial effect on the subjects. | - |
dc.description.sponsorship | Supported in part by Instituto de Salud Carlos III, “Red temática de Investigación Cooperativa, Proyecto RD16/0008. OftaRed: Prevención, detección precoz, tratamiento y rehabilitación de las patologías oculares”. | - |
dc.language.iso | en | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | Glaucoma | - |
dc.subject | Keratograph | - |
dc.subject | Non-penetrating deep sclerectomy | - |
dc.subject | Ocular hyperemia | - |
dc.subject | Ocular surface disease | - |
dc.title | Changes in ocular surface after withdrawal of anti-glaucoma medications following non-penetrating deep sclerectomy | - |
dc.type | info:eu-repo/semantics/article | - |
dc.description.note | This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‑NonCommercial‑ShareAlike 4.0 License | - |
dc.identifier.doi | 10.4103/ijo.IJO_2654_21 | - |
dadun.citation.endingPage | 1633 | - |
dadun.citation.number | 5 | - |
dadun.citation.publicationName | Indian Journal of Ophthalmology | - |
dadun.citation.startingPage | 1626 | - |
dadun.citation.volume | 70 | - |
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