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dc.creatorSanz-de-Galdeano, A. (Anna)-
dc.creatorTerskaya, A. (Anastasia)-
dc.creatorUpegui, A. (Angie)-
dc.date.accessioned2023-02-20T10:35:33Z-
dc.date.available2023-02-20T10:35:33Z-
dc.date.issued2020-
dc.identifier.citationSanz-de-Galdeano, A. (Anna); Terskaya, A. (Anastasia); Upegui, A. (Angie). "Association of a genetic risk score with BMI along the life-cycle: Evidence from several US cohorts". PLOS ONE. 15 (9), 2020, e0239067es_ES
dc.identifier.issn1932-6203-
dc.identifier.urihttps://hdl.handle.net/10171/65508-
dc.description.abstractWe use data from the National Longitudinal Study of Adolescent to Adult Health and from the Health and Retirement Study to explore how the effect of individuals’ genetic predisposition to higher BMI —measured by BMI polygenic scores— changes over the life-cycle for several cohorts. We find that the effect of BMI polygenic scores on BMI increases significantly as teenagers transition into adulthood (using the Add Health cohort, born 1974-83). However, this is not the case for individuals aged 55+ who were born in earlier HRS cohorts (1931-53), whose life-cycle pattern of genetic influence on BMI is remarkably stable as they move into old-age.es_ES
dc.description.sponsorshipAnna Sanz-de-Galdeano acknowledges financial support from PROMETEO/2019/037 and from the Spanish Ministry of Economy and Competitiveness Grant ECO2017-87069-P.es_ES
dc.language.isoenges_ES
dc.publisherPLOSes_ES
dc.relationinfo:eu-repo/grantAgreement/AEI/Proyectos I+D/ECO2017-87069-P/ES/MICROECONOMIA APLICADA Y ECONOMIA FINANCIERA EMPIRICAes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectBMIes_ES
dc.subjectUS cohortses_ES
dc.subjectObesityes_ES
dc.subjectGeneticses_ES
dc.subjectPhenotypeses_ES
dc.titleAssociation of a genetic risk score with BMI along the life-cycle: evidence from several US cohortses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.description.noteThis is an open access article distributed under the terms of the Creative Commons Attribution Licensees_ES
dc.identifier.doi10.1371/journal.pone.0239067-
dadun.citation.number9es_ES
dadun.citation.publicationNamePLOS ONEes_ES
dadun.citation.startingPagee0239067es_ES
dadun.citation.volume15es_ES
dc.identifier.pmid32941506-

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