Full metadata record
DC Field | Value | Language |
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dc.creator | Goñi-Mateos, L. (Leticia) | - |
dc.creator | Sun, D. (Dianjianyi) | - |
dc.creator | Heianza, Y. (Yoriko) | - |
dc.creator | Wang, T. (Tiange) | - |
dc.creator | Huang, T. (Tao) | - |
dc.creator | Cuervo, M. (Marta) | - |
dc.creator | Martinez, J.A. (José Alfredo) | - |
dc.creator | Shang, X. (Xiaoyun) | - |
dc.creator | Bray, G.A. (George A.) | - |
dc.creator | Sacks, F.M. (Frank M.) | - |
dc.creator | Qi, L. (Lu) | - |
dc.date.accessioned | 2023-03-06T11:30:34Z | - |
dc.date.available | 2023-03-06T11:30:34Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Goni, L. (Leticia); Sun, D. (Dianjianyi); Heianza, Y. (Yoriko); et al. "Macronutrient-specific effect of the MTNR1B genotype on lipid levels in response to 2 year weight-loss diets". Journal of lipid research. 59 (1), 2018, 155 - 161 | es_ES |
dc.identifier.issn | 0022-2275 | - |
dc.identifier.uri | https://hdl.handle.net/10171/65620 | - |
dc.description.abstract | Compelling evidence indicates that lipid metabolism is in partial control of the circadian system. In this context, it has been reported that the melatonin receptor 1B (MTNR1B) genetic variant influences the dynamics of melatonin secretion, which is involved in the circadian system as a chronobiotic. The objective was to analyze whether the MTNR1B rs10830963 genetic variant was related to changes in lipid levels in response to dietary interventions with different macronutrient distribution in 722 overweight/obese subjects from the POUNDS Lost trial. We did not find a significant association between the MTNR1B genotype and changes in lipid metabolism. | es_ES |
dc.description.sponsorship | This work was supported by National Heart, Lung, and Blood Institute Grants HL071981, HL034594, and HL126024; National Institute of Diabetes and Digestive and Kidney Diseases Grants DK091718, DK100383, and DK078616; Boston Obesity Nutrition Research Center Grant DK46200; and United States-Israel Binational Science Foundation Grant 2011036. L.G. is a recipient of predoctoral and mobility grants from the Spanish Ministry of Education, Culture, and Sport. Y.H. is a recipient of a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science. L.Q. was a recipient of American Heart Association Scientist Development Award 0730094N. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | American Society for Biochemistry and Molecular Biology | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Cholesterol | es_ES |
dc.subject | Clinical trials | es_ES |
dc.subject | Diet and dietary lipids | es_ES |
dc.subject | Gene-diet interaction | es_ES |
dc.subject | Genetics | es_ES |
dc.subject | High-fat diet | es_ES |
dc.subject | Lipid metabolism | es_ES |
dc.subject | Low density lipoprotein | es_ES |
dc.subject | Melatonin receptor 1B | es_ES |
dc.subject | Weight-loss intervention | es_ES |
dc.title | Macronutrient-specific effect of the MTNR1B genotype on lipid levels in response to 2 year weight-loss diets | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.description.note | This is an Open Access article under the CC BY license. | es_ES |
dc.identifier.doi | 10.1194/jlr.P078634 | - |
dadun.citation.endingPage | 161 | es_ES |
dadun.citation.number | 1 | es_ES |
dadun.citation.publicationName | Journal of lipid research | es_ES |
dadun.citation.startingPage | 155 | es_ES |
dadun.citation.volume | 59 | es_ES |
dc.identifier.pmid | 29089366 | - |
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