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dc.creatorRodríguez-Garijo, N. (Nuria)-
dc.creatorSabaté-Brescó, M. (Marina)-
dc.creatorAzofra, J. (Julián)-
dc.creatorBaeza, M.L. (María Luisa)-
dc.creatorDiaz-Donado, C. (Carmen)-
dc.creatorGaig, P. (Pere)-
dc.creatorGuilarte, M. (Mar)-
dc.creatorHerrera-Lasso, V. (Valeria)-
dc.creatorLabrador-Horrillo, M. (Moises)-
dc.creatorSala-Cunill, A. (Anna)-
dc.creatorVeleiro, B. (Beatriz)-
dc.creatorGil, M.P. (María Pilar)-
dc.creatorFerrer-Cardona, M. (Marta)-
dc.identifier.citationRodríguez-Garijo, N. (Nuria); Sabaté-Brescó, M. (Marina); Azofra, J. (Julián); et al. "Angioedema severity and impact on quality of life: Chronic histaminergic angioedema versus chronic spontaneous urticaria". The Journal of Allergy and Clinical Immunology: In Practice. 10 (11), 2022, 3039 - 3043.e3es_ES
dc.description.abstractHistamine-mediated angioedema is the most frequent form of angioedema. It is classified as idiopathic histaminergic acquired angioedema (IH-AAE)1 when allergies and other causes have been excluded and a positive treatment response to antihistamines, corticosteroids, or omalizumab has been reported. Idiopathic histaminergic acquired angioedema may occur in isolation, when it is termed chronic histaminergic angioedema (CHA), or it may be associated with wheals in chronic spontaneous urticaria angioedema (CSU-AE). The term CHA is equivalent to IH-AAE and mast cell-mediated angioedema. However, this term reflects the chronic and recurrent course of the disease. Therefore, we propose that the term CHA be internationally discussed in the following guidelines. Chronic spontaneous urticaria is classically characterized by the presence of recurrent episodes of wheals (hives) with or without angioedema for at least 6 weeks.2 Chronic histaminergic angioedema is typically considered a subtype of CSU without wheals. However, a recent study3 found several features that differentiate CHA from CSU, which suggests that CHA is a separate entity. Quality of life (QoL) studies specifically for CHA patients have not been performed, and their QoL has been assessed only in the context of CSU-AE.es_ES
dc.description.sponsorshipThis work was supported by Grants PI16/01304 and #PI20/ 01536 from the Instituto de Salud Carlos III and the Thematic Networks for Co-operative Research Centers: Reacciones Adversas y Alérgicas network (RD16/0006/0031) from Instituto de Salud Carlos III, cofounded by Fondo Europeo de Desarrollo Regional.es_ES
dc.subjectChronic histaminergic angioedemaes_ES
dc.subjectChronic spontaneous urticariaes_ES
dc.subjectQuality of lifees_ES
dc.titleAngioedema severity and impact on quality of life: Chronic histaminergic angioedema versus chronic spontaneous urticariaes_ES
dc.description.noteThis is an open access article distributed under the terms of the Creative Commons CC-BY licensees_ES
dadun.citation.publicationNameThe Journal of Allergy and Clinical Immunology: In Practicees_ES

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