Sarcomatoid tumor Spindle cell carcinoma Vocal fold lesion Cancer larynx
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Fernández, S. (Secundino); Ferran, S. (Sol); Alcalde, J. (Juan); et al. "Spindle cell carcinoma: Two instances mistaken for vocal polyps". Otolaryngology Case Reports. 26, 2023, 100503
Spindle cell carcinoma is a variant of squamous carcinoma, with
behavior that is apparently more aggressive than that of squamous
carcinoma and that can produce distant lymphatic metastasis.
It was first described by Virchow in 1864 , but the origin of the
tumor is still not clear. The tumor is biphasic, with an epidermal
component and a sarcomatous component involving spindle cells;
transition zones between these components can be found [2–5]. In part
due to this peculiar and complex nature, the tumor has accumulated
various names since it was first described: sarcomatoid tumor, carci-
nosarcoma, pleomorphic carcinoma, collision tumor, etc. [2,5,6].