American heart association's life simple 7 and the risk of atrial fibrillation in the PREDIMED study cohort
Keywords: 
Atrial fibrillation
Life simple 7
Cardiovascular health
Lifestyle
Cardiovascular disease prevention
PREDIMED
Issue Date: 
2023
Publisher: 
Elsevier
Project: 
info:eu-repo/grantAgreement/MSC/Redes Temáticas de Investigación Cooperativa en Salud (RETICS)/RD06/0045/0000/[ES]/ALIMENTACIÓN SALUDABLE EN LA PREVENCIÓN PRIMARIA DE ENFERMEDADES CRÓNICAS: LA RED PREDIMED
ISSN: 
1590-3729
36958970
Note: 
This is an open access article under the CC BY-NC-ND license
Citation: 
Diaz-Gutierrez, J. (Jesús); Martinez-Gonzalez, M.A. (Miguel Ángel); Alonso, A. (Alvaro); et al. "American heart association's life simple 7 and the risk of atrial fibrillation in the PREDIMED study cohort". Nutrition, Metabolism and Cardiovascular Diseases. 33 (6), 2023, 1144 - 1148
Abstract
Background and aims The American Heart Association proposed 7 ideal cardiovascular health metrics (Life's Simple 7 [LS7]) namely, not smoking, body mass index <25 kg/m2, healthy diet, moderate physical activity ≥150 min/week, total blood cholesterol <200 mg/dL, blood pressure <120/80 mmHg and fasting blood glucose <100 mg/dL. Our objective was to assess the association between these LS7 metrics and the incidence of atrial fibrillation (AF). Methods and results A total of 6,479 participants of the PREDIMED study were included. We calculated the participants’ baseline LS7 index ranging 0–7 points to categorize them according to their adherence to these LS7 health metrics. Multivariable Cox regression models were used to estimate Hazard Ratios (HR) and their 95% Confidence Intervals (95% CI). After a median follow-up of 4.8 years, we identified 250 incident cases of AF. After adjusting for potential confounders, adherence to LS7 index was not associated with the incidence of AF (adjusted HR 0.90 [95% CI: 0.56–1.45] for highest vs. lowest LS7 categories). Body mass index <25 kg/m2 was the only health metric individually associated with a lower risk of AF (HR 0.36 [95% CI: 0.16–0.78]). Conclusions In a high cardiovascular risk Spanish population, adherence to American Heart Association's LS7 metrics was not associated with the risk of incident AF.

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