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dc.creatorMøller, P. (Peter)-
dc.creatorAzqueta, A. (Amaya)-
dc.creatorBoutet-Robinet, E. (Elisa)-
dc.creatorKoppen, G. (Gudrun)-
dc.creatorBonassi, S. (Stefano)-
dc.creatorMilic, M. (Mirta)-
dc.creatorGajski, G. (Goran)-
dc.creatorCosta, S. (Solange)-
dc.creatorTeixeira, J.P. (Joao Paulo)-
dc.creatorCosta-Pereira, C. (Cristiana)-
dc.creatorDusinska, M. (Maria)-
dc.creatorGodschalk, R. (Roger)-
dc.creatorBrunborg, G. (Gunnar)-
dc.creatorGützkow, K.B. (Kristine Bjerve)-
dc.creatorGiovannelli, L. (Lisa)-
dc.creatorCooke, M.S. (Marcus S.)-
dc.creatorRichling, E. (Elke)-
dc.creatorLaffon, B. (Blanca)-
dc.creatorValdiglesias, V. (Vanessa)-
dc.creatorBasaran, N. (Nursen)-
dc.creatorDel-Bo, C. (Cristian)-
dc.creatorZegura, B. (Bojana)-
dc.creatorNovak, M. (Matjaz)-
dc.creatorStopper, H. (Helga)-
dc.creatorVodicka, P. (Pavel)-
dc.creatorVodenkova, S. (Sona)-
dc.creatorMoraes-de-Andrade, V. (Vanessa)-
dc.creatorSramkova, M. (Monika)-
dc.creatorGabelova, A. (Alena)-
dc.creatorCollins, A. (Andrew)-
dc.creatorLangie, S.A.S. (Sabine A. S.)-
dc.identifier.citationMöller, P. (Peter); Azqueta, A. (Amaya); Boutet-Robinet, E. (Elisa); et al. "Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results". Nature Protocols. 15, 2020, 3817 - 3826es
dc.description.abstractThe comet assay is a widely used test for the detection of DNA damage and repair activity. However, there are interlaboratory differences in reported levels of baseline and induced damage in the same experimental systems. These differences may be attributed to protocol differences, although it is difficult to identify the relevant conditions because detailed comet assay procedures are not always published. Here, we present a Consensus Statement for the Minimum Information for Reporting Comet Assay (MIRCA) providing recommendations for describing comet assay conditions and results. These recommendations differentiate between ‘desirable’ and ‘essential’ information: ‘essential’ information refers to the precise details that are necessary to assess the quality of the experimental work, whereas ‘desirable’ information relates to technical issues that might be encountered when repeating the experiments. Adherence to MIRCA recommendations should ensure that comet assay results can be easily interpreted and independently verified by other researchers.es_ES
dc.titleMinimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and resultses_ES
dc.description.noteThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.es_ES
dc.editorial.noteSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.es_ES
dadun.citation.publicationNameNature Protocolses_ES

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