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dc.creatorDe-Benedetto, L. (Luigi)-
dc.creatorMoffa, A. (Antonio)-
dc.creatorBaptista-Jardin, P. (Peter)-
dc.creatorDi-Giovanni, S. (Simone)-
dc.creatorGiorgi, L. (Lucrezia)-
dc.creatorVerri, M. (Martina)-
dc.creatorTaffon, C. (Chiara)-
dc.creatorCrescenzi, A. (Anna)-
dc.creatorCasale-Falcone, M. (Manuele)-
dc.date.accessioned2023-11-02T11:10:11Z-
dc.date.available2023-11-02T11:10:11Z-
dc.date.issued2023-
dc.identifier.citationDe Benedetto, L.; Moffa, A.; Baptista-Jardín, P. (Peter Michael); et al. "Potential Use of Vivascope for real-time histological evaluation in endoscopic laryngeal surgery". Journal of personalized medicine. 13 (8), 2023, 1252es
dc.identifier.citationDe Benedetto, L.; Moffa, A.; Baptista-Jardín, P. (Peter Michael); et al. "Potential Use of Vivascope for real-time histological evaluation in endoscopic laryngeal surgery". Journal of personalized medicine. 13 (8), 2023, 1252es
dc.identifier.issn2075-4426-
dc.identifier.urihttps://hdl.handle.net/10171/67794-
dc.description.abstractWe aimed to assess the feasibility of using confocal laser scanning microscopy (CLSM) for the real-time ex vivo examination of histological samples of laryngeal lesions and to evaluate the correlation between CLSM and definitive histological results. This preliminary study included eight consecutive patients with suspected laryngeal lesions who were candidates for endoscopic laryngeal surgery. The obtained samples were evaluated using CLSM and classified as inadequate or adequate (high- and low-grade dysplasia, in situ and invasive carcinoma, positive surgical margin, and inflammatory outbreaks). CLSM showed the macro image in all cases and generated a digital version. All the samples were defined as adequate during CLSM and confirmed at histopathology: low-grade dysplasia (n = 5), low- and high-grade dysplasia (n = 2), and high-grade dysplasia (n = 1). Four samples had an involved resection margin, and three samples revealed the presence of inflammatory outbreaks. CLSM can be applied to larynx pathology with excellent agreement with final histological results.-
dc.language.isoen-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.subjectÁrea de Medicina Clínica y Epidemiología-
dc.subjectLaryngeal dysplasia-
dc.subjectArtificial intelligence-
dc.subjectEndoscopic laryngeal surgery-
dc.subjectConfocal laser scanning microscopy-
dc.titlePotential Use of Vivascope for real-time histological evaluation in endoscopic laryngeal surgery-
dc.typeinfo:eu-repo/semantics/article-
dc.relation.publisherversionhttps://pubmed.ncbi.nlm.nih.gov/37623502/-
dc.description.noteThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).-
dc.identifier.doi10.3390/jpm13081252-
dadun.citation.number8-
dadun.citation.publicationNameJOURNAL OF PERSONALIZED MEDICINE-
dadun.citation.startingPage1252-
dadun.citation.volume13-
dc.identifier.pmid37623502-

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