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dc.creatorPortincasa, P. (Piero)-
dc.creatorFrühbeck, G. (Gema)-
dc.date.accessioned2023-11-21T12:53:45Z-
dc.date.available2023-11-21T12:53:45Z-
dc.date.issued2023-
dc.identifier.citationPortincasa, P. (Piero); Frühbeck, G. (Gema). "Phenotyping the obesities: reality or utopia?". Reviews in Endocrine and Metabolic Disorders. 24 (5), 2023, 767 - 773es_ES
dc.identifier.issn1573-2606-
dc.identifier.urihttps://hdl.handle.net/10171/67925-
dc.description.abstractIn this thematic issue on phenotyping the obesities, prominent international experts offer an insightful and comprehensive collection of articles covering the current knowledge in the field. In order to actually capture all the polyhedral determinants of the diverse types of obesity, the granularity of the phenotypic information acquired must be expanded in the context of a personalized approach. Whilst the use of precision medicine has been successfully implemented in areas like cancer and other diseases, health care providers are more reluctant to embrace detailed phenotyping to guide diagnosis, treatment and prevention in obesity. Given its multiple complex layers, phenotyping necessarily needs to go beyond the multi-omics approach and incorporate all the diverse spheres that conform the reality of people living with obesity. Potential barriers, difficulties, roadblocks and opportunities together with their interaction in a syndemic context are analyzed. Plausible lacunae are also highlighted in addition to pointing to the need of redefining new conceptual frameworks. Therefore, this extraordinary collection of state-ofthe-art reviews provides useful information to both experienced clinicians and trainees as well as academics to steer clinical practice and research in the management of people living with obesity irrespective of practice setting or career stage.es_ES
dc.description.sponsorshipOpen Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. Supported by Plan Estatal I+D+I from the Spanish Instituto de Salud Carlos III–Subdirección General de Evaluación y Fomento de la investigación–FEDER (grant number PI22/00745) and CIBEROBN, ISCIII, Spain.es_ES
dc.language.isoenges_ES
dc.publisherSpringeres_ES
dc.relationinfo:eu-repo/grantAgreement/ISCIII/PI22- Proyectos de I+D+I en salud (AES 2022)./PI22/00745/[ES]/Cambios en la inflamación del tejido adiposo asociada a la obesidad y sus comorbilidades tras cirugía bariátrica inducidos por la proteína 1 similar a la folistatina (FSTL1)es_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectClusteringes_ES
dc.subjectComorbiditieses_ES
dc.subjectHeterogeneityes_ES
dc.subjectObesityes_ES
dc.subjectPatient stratificationes_ES
dc.subjectPhenotypeses_ES
dc.titlePhenotyping the obesities: reality or utopia?es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.description.noteThis article is licensed under a Creative Commons Attribution 4.0 International Licensees_ES
dc.identifier.doi10.1007/s11154-023-09829-x-
dadun.citation.endingPage773es_ES
dadun.citation.number5es_ES
dadun.citation.publicationNameReviews in Endocrine and Metabolic Disorderses_ES
dadun.citation.startingPage767es_ES
dadun.citation.volume24es_ES
dc.identifier.pmid37537402-

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