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dc.creatorGarcia-Velloso, M. J. (María José)-
dc.creatorRibelles, M.J. (María Jesús)-
dc.creatorRodriguez, M. (Macarena)-
dc.creatorFernandez-Montero, A. (Alejandro)-
dc.creatorSancho, L. (Lidia)-
dc.creatorPrieto, E. (Elena)-
dc.creatorSantisteban, M. (Marta)-
dc.creatorRodriguez-Spiteri, N. (Natalia)-
dc.creatorIdoate, M.A. (Miguel Ángel)-
dc.creatorMartinez-Regueira, F. (Fernando)-
dc.creatorElizalde, A. (Arlette)-
dc.creatorPina, L. (Luis)-
dc.date.accessioned2024-02-09T11:51:44Z-
dc.date.available2024-02-09T11:51:44Z-
dc.date.issued2017-
dc.identifier.citationGarcia-Velloso, M. J. (María José); Ribelles, M.J. (María Jesús); Rodriguez, M. (Macarena); et al. "MRI fused with prone FDG PET/CT improves the primary tumour staging of patients with breast cancer". European Radiology. 27 (8), 2017, 3190 - 3198es
dc.identifier.issn0720-048X-
dc.identifier.urihttps://hdl.handle.net/10171/68981-
dc.description.abstractObjective: Our aim was to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) fused with prone 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) in primary tumour staging of patients with breast cancer. Methods: This retrospective study evaluated 45 women with 49 pathologically proven breast carcinomas. MRI and prone PET-CT scans with time-of-flight and point-spread-function reconstruction were performed with the same dedicated breast coil. The studies were assessed by a radiologist and a nuclear medicine physician, and evaluation of fused images was made by consensus. The final diagnosis was based on pathology (90 lesions) or follow-up ≥ 24 months (17 lesions). Results: The study assessed 72 malignant and 35 benign lesions with a median size of 1.8 cm (range 0.3-8.4 cm): 31 focal, nine multifocal and nine multicentric cases. In lesion-by-lesion analysis, sensitivity, specificity, positive and negative predictive values were 97%, 80%, 91% and 93% for MRI, 96%, 71%, 87%, and 89% for prone PET, and 97%. 94%, 97% and 94% for MRI fused with PET. Areas under the curve (AUC) were 0.953, 0.850, and 0.983, respectively (p < 0.01). Conclusions: MRI fused with FDG-PET is more accurate than FDG-PET in primary tumour staging of breast cancer patients and increases the specificity of MRI.es_ES
dc.description.sponsorshipThis study has received funding by the Government of Spain, Institute of Health Carlos III, Ministry of Science and Innovation (Project ADE 10/ 00028).es_ES
dc.language.isoenges_ES
dc.publisherSpringeres_ES
dc.rightsinfo:eu-repo/semantics/embargoedAccess*
dc.subjectBreast canceres_ES
dc.subjectFDGes_ES
dc.subjectMagnetic resonance imaging (MRI)es_ES
dc.subjectProne positron emission tomography computed tomography (PET-CT)es_ES
dc.subjectStaginges_ES
dc.titleMRI fused with prone FDG PET/CT improves the primary tumour staging of patients with breast canceres_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.identifier.doi10.1007/s00330-016-4685-8-
dadun.citation.endingPage3198es_ES
dadun.citation.number8es_ES
dadun.citation.publicationNameEuropean Radiologyes_ES
dadun.citation.startingPage3190es_ES
dadun.citation.volume27es_ES
dc.identifier.pmid28004161-

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