Martinez, J.A. (José Alfredo)Grijalba, A.M. (A. M.)García-Unciti, M.S. (María Soledad)Izquierdo, M. (Mikel)Santos, J. (Javier)Gorostiaga, E. (Esteban)2013-03-292013-03-292012Garcia-Unciti M, Martinez JA, Izquierdo M, Gorostiaga EM, Grijalba A, Ibanez J. Effect of resistance training and hypocaloric diets with different protein content on body composition and lipid profile in hypercholesterolemic obese women. Nutr Hosp 2012 Oct;27(5):1511-15200212-1611https://hdl.handle.net/10171/28197Lifestyle changes such as following a hypocaloric diet and regular physical exercise are recognized as effective non-pharmacological interventions to reduce body fat mass and prevent cardiovascular disease risk factors. Purpose: To evaluate the interactions of a higher protein (HP) vs. a lower protein (LP) diet with or without a concomitant progressive resistance training program (RT) on body composition and lipoprotein profile in hypercholesterolemic obese women. Methods: Retrospective study derived from a 16-week randomized controlled-intervention clinical trial. Twentyfive sedentary, obese (BMI: 30-40 kg/m²) women, aged 40-60 with hypercholesterolemia were assigned to a 4-arm trial using a 2 x 2 factorial design (Diet x Exercise). Prescribed diets had the same calorie restriction (-500 kcal/day), and were categorized according to protein content as: lower protein (< 22% daily energy intake, LP) vs. higher protein (> 22% daily energy intake, HP). Exercise comparisons involved habitual activity (control) vs. a 16-week supervised whole-body resistance training program (RT), two sessions/wk. Results: A significant decrease in weight and waist circumference was observed in all groups. A significant decrease in LDL-C and Total-Cholesterol levels was observed only when a LP diet was combined with a RT program, the RT being the most determining factor. Interestingly, an interaction between diet and exercise was found concerning LDL-C values. Conclusion: In this study, resistance training plays a key role in improving LDL-C and Total-Cholesterol; however, a lower protein intake (< 22% of daily energy intake as proteins) was found to achieve a significantly greater reduction in LDL-C.enginfo:eu-repo/semantics/openAccessDietObesityLipid metabolismResistance trainingEffect of resistance training and hypocaloric diets with different protein content on body composition and lipid profile in hypercholesterolemic obese womenEfecto de un entrenamiento de fuerza y dieta hipocalórica con diferente aporte proteico sobre la composición corporal y el perfil lipídico en mujeres obesas con hipercolesterolemiainfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3305/nh.2012.27.5.5921