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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.creator | Aranda, A. (Alejandro) | - |
dc.creator | Paramo, J.A. (José Antonio) | - |
dc.creator | Rocha, E. (Eduardo) | - |
dc.date.accessioned | 2012-05-08T09:50:37Z | - |
dc.date.available | 2012-05-08T09:50:37Z | - |
dc.date.issued | 1988 | - |
dc.identifier.citation | Aranda A, Paramo JA, Rocha E. Fibrinolytic activity in plasma after gynecological and urological surgery. Haemostasis 1988;18(2):129-134. | es_ES |
dc.identifier.issn | 1423-0038 | - |
dc.identifier.uri | https://hdl.handle.net/10171/21968 | - |
dc.description.abstract | Fibrinolytic activity was studied in 51 patients subjected to major surgery (27 urological and 24 gynecological) without prophylaxis. Postoperative deep-vein thrombosis (DVT) was diagnosed by venography in 6 patients (11%). Blood samples were obtained preoperatively and on days 1, 3 and 7 postoperatively. Reduced fibrinolytic activity, as determined by prolongation of euglobulin lysis time (ELT), decrease in plasminogen activators on fibrin plate and decrease in tissue-type plasminogen activator (t-PA) activity were present postoperatively. Moreover, a marked increase in short duration in fast-acting inhibitor (PA-inhibitor) levels was observed on postoperative day 1 (p less than 0.001). Patients with DVT had higher fibrinogen degradation product (FDP) levels on postoperative days 3 and 7 (p less than 0.02). Preoperative PA-inhibitor activity was higher (p less than 0.02) in those patients who developed postoperative DVT. It is concluded that the decrease in t-PA and the increase in PA-inhibitor may contribute to the reduced postoperative fibrinolytic activity after major surgery. PA-inhibitor may represent a useful predictive marker of postoperative DVT. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Karger | es_ES |
dc.rights | info:eu-repo/semantics/closedAccess | - |
dc.subject | Genital Diseases, Female/surgery | es_ES |
dc.subject | Postoperative Complications/blood | es_ES |
dc.subject | Urologic Diseases/surgery | es_ES |
dc.title | Fibrinolytic activity in plasma after gynecological and urological surgery | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | http://bit.ly/JbKw2O | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
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