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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.creator | Moreno-Navarrete, J. (José) | - |
dc.creator | Catalan, V. (Victoria) | - |
dc.creator | Ortega, F.J. (Francisco J.) | - |
dc.creator | Gomez-Ambrosi, J. (Javier) | - |
dc.creator | Ricart, W. (Wifredo) | - |
dc.creator | Frühbeck, G. (Gema) | - |
dc.creator | Fernandez-Real, J.M. (José Manuel) | - |
dc.date.accessioned | 2012-09-26T11:59:39Z | - |
dc.date.available | 2012-09-26T11:59:39Z | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | Moreno-Navarrete JM, Catalan V, Ortega F, Gomez-Ambrosi J, Ricart W, Fruhbeck G, et al. Circulating omentin concentration increases after weight loss. Nutr Metab (Lond) 2010 Apr 9;7:27. | es_ES |
dc.identifier.issn | 1743-7075 | - |
dc.identifier.uri | https://hdl.handle.net/10171/23231 | - |
dc.description.abstract | Omentin-1 is a novel adipokine expressed in visceral adipose tissue and negatively associated with insulin resistance and obesity. We aimed to study the effects of weight loss-induced improved insulin sensitivity on circulating omentin concentrations. METHODS: Circulating omentin-1 (ELISA) concentration in association with metabolic variables was measured in 35 obese subjects (18 men, 17 women) before and after hypocaloric weight loss. RESULTS: Baseline circulating omentin-1 concentrations correlated negatively with BMI (r = -0.58, p < 0.001), body weight (r = -0.35, p = 0.045), fat mass (r = -0.67, p < 0.001), circulating leptin (r = -0.7, p < 0.001) and fasting insulin (r = -0.37, p = 0.03). Circulating omentin-1 concentration increased significantly after weight loss (from 44.9 +/- 9.02 to 53.41 +/- 8.8 ng/ml, p < 0.001). This increase in circulating omentin after weight loss was associated with improved insulin sensitivity (negatively associated with HOMA value and fasting insulin, r = -0.42, p = 0.02 and r = -0.45, p = 0.01, respectively) and decreased BMI (r = -0.54, p = 0.001). CONCLUSION: As previously described with adiponectin, circulating omentin-1 concentrations increase after weight loss-induced improvement of insulin sensitivity. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | BioMed Central | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Weight loss | es_ES |
dc.subject | Circulating omentin | es_ES |
dc.title | Circulating omentin concentration increases after weight loss | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | http://www.nutritionandmetabolism.com/content/pdf/1743-7075-7-27.pdf | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
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