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DC FieldValueLanguage
dc.creatorFrühbeck, G. (Gema)-
dc.creatorBurrell, M.A. (María Ángela)-
dc.creatorSesma, M.P. (María Pilar)-
dc.date.accessioned2010-09-16T09:53:47Z-
dc.date.available2010-09-16T09:53:47Z-
dc.date.issued2009-04-
dc.identifier.citationFruhbeck G, Sesma P, Burrell MA. PRDM16: the interconvertible adipo-myocyte switch. Trends Cell Biol 2009 Apr;19(4):141-146.es_ES
dc.identifier.issn0962-8924-
dc.identifier.urihttps://hdl.handle.net/10171/12568-
dc.description.abstractBoth brown and white adipocytes were previously considered to be derived from the same precursor cell, despite being histologically and functionally different. However, a recent study shows that overexpression of the transcriptional regulator positive regulatory domain containing 16 (PRDM16) determines the development of brown adipocytes from a progenitor that expresses myoblast markers. Surprisingly, loss of PRDM16 from these precursors does not lead to white adipocyte differentiation. Thus, PRDM16 controls a bidirectional cell fate switch between skeletal myoblasts and brown adipocyteses_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.rightsinfo:eu-repo/semantics/closedAccess-
dc.subjectInterconvertiblees_ES
dc.subjectAdipo-myocytees_ES
dc.subjectSwitches_ES
dc.titlePRDM16: The intercovertible adipo-myocyte switches_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.identifier.doihttp://dx.doi.org/10.1016/j.tcb.2009.01.007es_ES

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