Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Frühbeck, G. (Gema) | - |
dc.creator | Burrell, M.A. (María Ángela) | - |
dc.creator | Sesma, M.P. (María Pilar) | - |
dc.date.accessioned | 2010-09-16T09:53:47Z | - |
dc.date.available | 2010-09-16T09:53:47Z | - |
dc.date.issued | 2009-04 | - |
dc.identifier.citation | Fruhbeck G, Sesma P, Burrell MA. PRDM16: the interconvertible adipo-myocyte switch. Trends Cell Biol 2009 Apr;19(4):141-146. | es_ES |
dc.identifier.issn | 0962-8924 | - |
dc.identifier.uri | https://hdl.handle.net/10171/12568 | - |
dc.description.abstract | Both brown and white adipocytes were previously considered to be derived from the same precursor cell, despite being histologically and functionally different. However, a recent study shows that overexpression of the transcriptional regulator positive regulatory domain containing 16 (PRDM16) determines the development of brown adipocytes from a progenitor that expresses myoblast markers. Surprisingly, loss of PRDM16 from these precursors does not lead to white adipocyte differentiation. Thus, PRDM16 controls a bidirectional cell fate switch between skeletal myoblasts and brown adipocytes | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/closedAccess | - |
dc.subject | Interconvertible | es_ES |
dc.subject | Adipo-myocyte | es_ES |
dc.subject | Switch | es_ES |
dc.title | PRDM16: The intercovertible adipo-myocyte switch | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | http://dx.doi.org/10.1016/j.tcb.2009.01.007 | es_ES |
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