Pharmacokinetic–pharmacodynamic modelling of the analgesic effects of lumiracoxib, a selective inhibitor of cyclooxygenase-2, in rats
Keywords:
Pharmacokinetic/pharmacodynamic modelling
cyclooxygenase-2
Inflammatory mediators
Hyperalgesia
Time latency
Publisher:
British pharmacological society
Citation:
Vásquez-Bahena DA, Salazar-Morales UE, Ortiz MI, Castañeda-Hernández G, Trocóniz IF. Pharmacokinetic–pharmacodynamic modelling of the analgesic effects of lumiracoxib, a selective inhibitor of cyclooxygenase-2, in rats. Br J Pharmacol. 2010 Jan;159(1):176-87.
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