Guridi J, Rodriguez-Oroz MC, Manrique M. Tratamiento quirúrgico para la enfermedad de Parkinson. Neurocirugia (Astur) 2004 Feb;15(1):5-16.
In the past years there has been an increasing interest in the surgical therapies
for Parkinson's disease. This renewed interest is related to differents factors.
First, pharmacological treatments are still unable to alter substantially the
progression of the disease and after a few years they generally cause motor
complications and dyskinesias. Secondly, the great advances in the surgical
techniques, especially with the improvement of stereotactic surgery, have
decreased morbidity in recent years. Finally, the introduction of deep brain
stimulation, now allows surgical treatment without damaging brain structures. In
this review, different surgical treatments are summarized. Ablative surgery, deep
brain stimulation and reinervation therapies are described