Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Rubio-Baines, I. (I.) | - |
dc.creator | Honorato-Cía, C. (Cristina) | - |
dc.creator | Valencia, M. (Miguel) | - |
dc.creator | Panadero-Sánchez, A. (Alfredo) | - |
dc.creator | Cacho-Asenjo, E. (Elena) | - |
dc.creator | Manzanilla-Zapata, Ó. (Óscar) | - |
dc.creator | Alegre-Esteban, M. (Manuel) | - |
dc.creator | Nuñez-Cordoba, J.M. (Jorge M.) | - |
dc.creator | Martinez-Simon, A. (Antonio) | - |
dc.date.accessioned | 2023-09-21T09:41:14Z | - |
dc.date.available | 2023-09-21T09:41:14Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Rubio-Baines, I. (I.); Honorato-Cía, C. (Cristina); Valencia, M. (Miguel); et al. "Effect of sugammadex on processed EEG parameters in patients undergoing robot-assisted radical prostatectomy". British Journal of Anaesthesia. 131 (3), 2023, 523 - 530 | es |
dc.identifier.issn | 1471-6771 | - |
dc.identifier.uri | https://hdl.handle.net/10171/67286 | - |
dc.description.abstract | Background: Sugammadex has been associated with increases in the bispectral index (BIS). We evaluated the effects of sugammadex administration on quantitative electroencephalographic (EEG) and electromyographic (EMG) measures. Methods: We performed a prospective observational study of adult male patients undergoing robot-assisted radical prostatectomy. All patients received a sevoflurane-based general anaesthetic and a continuous infusion of rocuronium, which was reversed with 2 mg kg1 of sugammadex i.v. BIS, EEG, and EMG measures were captured with the BIS Vista™ monitor. Results: Twenty-five patients were included in this study. Compared with baseline, BIS increased at 4e6 min (b coefficient: 3.63; 95% confidence interval [CI]: 2.22e5.04; P<0.001), spectral edge frequency 95 (SEF95) increased at 2e4 min (b coefficient: 0.29; 95% CI: 0.05e0.52; P¼0.016) and 4e6 min (b coefficient: 0.71; 95% CI: 0.47e0.94; P<0.001), and EMG increased at 4e6 min (b coefficient: 1.91; 95% CI: 1.00e2.81; P<0.001) after sugammadex administration. Compared with baseline, increased beta power was observed at 2e4 min (b coefficient: 93; 95% CI: 1e185; P¼0.046) and 4e6 min (b coefficient: 208; 95% CI: 116e300; P<0.001), and decreased delta power was observed at 4e6 min (b coefficient: 526.72; 95% CI: 778 to 276; P<0.001) after sugammadex administration. Neither SEF95 nor frequency band data analysis adjusted for EMG showed substantial differences. None of the patients showed clinical signs of awakening. Conclusions: After neuromuscular block reversal with 2 mg kg1 sugammadex, BIS, SEF95, EMG, and beta power showed small but statistically significant increases over time, while delta power decreased. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Bispectral index | es_ES |
dc.subject | Depth of anaesthesia monitors | es_ES |
dc.subject | Electroencephalogram | es_ES |
dc.subject | Frequency bands | es_ES |
dc.subject | Spectral edge frequency | es_ES |
dc.subject | Sugammadex | es_ES |
dc.title | Effect of sugammadex on processed EEG parameters in patients undergoing robot-assisted radical prostatectomy | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.description.note | This is an open access article under the CC BY-NC-ND license | es_ES |
dc.identifier.doi | 10.1016/j.bja.2023.06.001 | - |
dadun.citation.endingPage | 530 | es_ES |
dadun.citation.number | 3 | es_ES |
dadun.citation.publicationName | British Journal of Anaesthesia | es_ES |
dadun.citation.startingPage | 523 | es_ES |
dadun.citation.volume | 131 | es_ES |
dc.identifier.pmid | 37422414 | - |
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