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Dadun > Depósito Académico > CIMA (Centro de Investigación Médica Aplicada) > Área de Ciencias Cardiovasculares > Aterosclerosis e inflamación > DA - CIMA - Cardiovasculares - Aterosclerosis e inflamación - Artículos de revista >

Fibrinogen and fibrin degradation products in patients undergoing open-heart surgery
Autor(es) : Rifon, J. (Jose)
Fernandez, J. (Javier)
Paramo, J.A. (José Antonio)
Cuesta, B. (Braulia)
Rocha, E. (Eduardo)
Palabras clave : Cardiac surgery
Fibrinogen degradation products
Fibrin degradation products
Fibrinogen
Fecha incorporación: 1990
Editorial : Lippincott, Williams & Wilkins
Versión del editor: http://bit.ly/NCPwBX
ISSN: 1473-5733
Cita: Rifon J, Fernandez J, Paramo JA, Cuesta B, Rocha E. Fibrinogen and fibrin degradation products in patients undergoing open-heart surgery. Blood Coagul Fibrinolysis 1990 Oct;1(4-5):509-512.
Resumen
We have determined fibrinogen and fibrin degradation products (FgDP and FbDP respectively) by an ELISA method using specific monoclonal antibodies in 100 patients undergoing cardiopulmonary bypass (CPB) for valvular heart disease and in 60 patients undergoing aorto-coronary bypass surgery. Blood samples were taken pre-operatively and on post-operative days 1 and 5. Post-operative evolution was similar in both patient groups, with a significant increase in FgDP on post-operative days 1 and 5 with respect to baseline value (P less than 0.01). FbDP were also significantly higher on post-operative days 1 and 5 (P less than 0.001), especially the day after surgery in patients with valvular disease as compared with coronary patients (P less than 0.01). Our results indicate that fibrinolysis is more important than fibrinogenolysis after open-heart surgery, which may have pathophysiological implications.
Enlace permanente: http://hdl.handle.net/10171/22818
Aparece en las colecciones: DA - CUN - Hematología y Hemoterapia - Artículos de revista
DA - CIMA - Cardiovasculares - Aterosclerosis e inflamación - Artículos de revista

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