Saralegui, I. (Iñaki)

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    Limitation of life support techniques at admission to the intensive care unit: a multicenter prospective cohort study
    (BioMed Central, 2018) Prieto, A. (Ana); Tizon, A.I. (Ana Isabel); Guía, C. (Consuelo); Martin, M. (Mar); Quesada, B. (Belen); Rubio, O. (Olga); Perea, M.E. (Maria Eugenia); Sánchez, J.M. (Juan María); Rascado, P. (Pedro); Forment-Fernández, M.M. (María del Mar); Marcos, A. (Alfredo); Catalan, R. (Rosa); Miro, G. (Gloria); Tomas, R. (Roser); Gómez, V. (Vicente); Balerdi, B. (Begoña); Montejo, J.C. (Juan Carlos); Saralegui, I. (Iñaki); Torrejon, C. (Cristina); Subirà, C. (Carles); Gomez, J.M. (José Manuel); Arauzo, V. (Vanesa); Poyo, R. (Rosa); Barber, M. (Maria); Sprung, C. (Charles); Monedero, P. (Pablo); Paz, M. (Marta); Mancebo, J. (Jordi); Fernández-Vivas, M. (Miguel); Zabala, E. (Elisabeth); Hernandez, G. (Gonzalo); Ortega-Montes, A. (Ana); Planas, K. (Kenneth); Cano, S. (Silvia); Español, V. (Valentí); Llamas, N. (Noemi); Añón, J.M. (José M.); Gonzalez, J. (Javier); Murcia, C. (Cristina); Xirgú, J. (Judith); Perez, J.M. (José Miguel); Fernandez, R. (Rafael); Altaba, S. (Susana); Arnau, A. (Anna)
    Purpose: To determine the frequency of limitations on life support techniques (LLSTs) on admission to intensive care units (ICU), factors associated, and 30-day survival in patients with LLST on ICU admission. Methods: This prospective observational study included all patients admitted to 39 ICUs in a 45-day period in 2011. We recorded hospitals’ characteristics (availability of intermediate care units, usual availability of ICU beds, and financial model) and patients’ characteristics (demographics, reason for admission, functional status, risk of death, and LLST on ICU admission (withholding/withdrawing; specific techniques affected)). The primary outcome was 30-day survival for patients with LLST on ICU admission. Statistical analysis included multilevel logistic regression models. Results: We recruited 3042 patients (age 62.5 ± 16.1 years). Most ICUs (94.8%) admitted patients with LLST, but only 238 (7.8% [95% CI 7.0–8.8]) patients had LLST on ICU admission; this group had higher ICU mortality (44.5 vs. 9.4% in patients without LLST; p < 0.001). Multilevel logistic regression showed a contextual effect of the hospital in LLST on ICU admission (median OR = 2.30 [95% CI 1.59–2.96]) and identified the following patient-related variables as independent factors associated with LLST on ICU admission: age, reason for admission, risk of death, and functional status. In patients with LLST on ICU admission, 30-day survival was 38% (95% CI 31.7–44.5). Factors associated with survival were age, reason for admission, risk of death, and number of reasons for LLST on ICU admission. Conclusions: The frequency of ICU admission with LLST is low but probably increasing; nearly one third of these patients survive for ≥ 30 days.
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    The state of transience, and its influence on the wish to die of advanced disease patients: insights from a qualitative phenomenological study
    (BioMed Central, 2024) Santesteban, Y. (Yolanda); Saralegui, I. (Iñaki); Centeno, C. (Carlos); Arantzamendi-Solabarrieta, M. (María); Alonso, N. (Nerea); Larkin, P. (Phil); Belar, A. (Alazne); Martínez, M. (Marina)
    Background: The experience of Wish to Die is common in patients living with Advanced Disease. It has been studied worldwide and qualitative studies have contributed to the understanding of the complexity of the phenomenon of the WTD but a deeper understanding on the individual's views is still needed. The objective of this study was to identify common characteristics of the experience of wish to die in advanced disease. Methods: A phenomenological study was carried out with multicenter participation of patients with advanced disease who had expressed their wish to die to health professionals. Semi-structured interviews were employed to obtain an in-depth perspective of each patient's lived experience. A phenomenological analysis of the data collected was performed to describe and explore the characteristic aspects of the phenomenon under study. Results: Fourteen patients with advanced disease were interviewed. Most of them had cancer. In the analysis of the patients' accounts of their experiences, three common characteristics were identified: a) experiencing a state of transience; b) the attempt to reconnect with oneself; and c) additional disease-related aspects that influence the wish to die. Patients expressed the need for a safe space to address the wish to die and the importance of receiving care that considers both 'being' and 'doing'. Conclusions: Patients with advanced disease and wish to die experience a state of transience where the patient lives and ephemeral state of existence. Interventions focused on reinforcing the intrinsic value of the individual emerge as essential components of a compassionate accompaniment of those facing the wish to die.