Oliver, D. (David)

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    Mediterranean alcohol-drinking pattern and arterial hypertension in the "Seguimiento Universidad de Navarra" (SUN) prospective cohort study
    (2023) Martinez-Gonzalez, M.A. (Miguel Ángel); Eguaras, S. (Sonia); Oliver, D. (David); Toledo, E. (Estefanía); Bes-Rastrollo, M. (Maira); Rosa-Fernández-Pacheco, P.A. (Pedro Antonio) de la; Hernandez-Hernandez, A. (Aitor); Ruiz-Canela, M. (Miguel); Gea, A. (Alfredo)
    Alcohol drinking patterns may determine the risk of hypertension and may also modify the detrimental effect of high alcohol intake. We prospectively evaluated the effect of the Mediterranean alcohol-drinking pattern and its interaction with the amount of alcohol consumed on the incidence of arterial hypertension. In the Seguimiento Universidad de Navarra (SUN) cohort, we followed-up 13,805 participants, all of them initially free of hypertension, during a maximum period of 16 years. Information about diet, chronic diseases, lifestyle and newly diagnosed hypertension was collected using validated questionnaires. We used a 7-item score (0 to 9 points) that jointly considered moderate alcohol consumption, distributed over the week, with meals, and a preference for red wine and avoidance of binge-drinking. During 142,404 person-years of follow-up, 1443 incident cases of hypertension were identified. Low adherence (score < 2) to the Mediterranean alcohol-drinking pattern was significantly associated with a higher incidence of hypertension (multivariable-adjusted hazard ratio 1.81, 95% confidence interval 1.09-2.99) as compared to the high-adherence (score > 7) category. Among alcohol consumers, a high adherence to the MADP is associated with a lower incidence of hypertension. Compared with abstinence, a high adherence did not seem to differ regarding its effect on hypertension risk.