Full metadata record
DC Field | Value | Language |
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dc.creator | Baptista-Jardin, P. (Peter) | - |
dc.creator | Di-Frisco, I.M. (Isberling Madeleine) | - |
dc.creator | Urrestarazu, E. (Elena) | - |
dc.creator | Alcalde, J. (Juan) | - |
dc.creator | Alegre-Esteban, M. (Manuel) | - |
dc.creator | Sánchez-Olivieri, I. (Isabel) | - |
dc.creator | O’Connor-Reina, C. (Carlos) | - |
dc.creator | Plaza, G. (Guillermo) | - |
dc.date.accessioned | 2023-04-19T13:04:27Z | - |
dc.date.available | 2023-04-19T13:04:27Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Baptista-Jardín, P. (Peter Michael); Di Frisco, I. (Isberling Madeleine); Urrestarazu-Bolumburu, E. (Elena); et al. "Quality of life impact of hypoglossal nerve stimulation with inspire (R) device in patients with obstructive sleep apnea intolerant to continuous positive airway pressure therapy". Life. 12 (11), 2022, 1737 | es |
dc.identifier.issn | 2075-1729 | - |
dc.identifier.uri | https://hdl.handle.net/10171/66026 | - |
dc.description.abstract | Patients with obstructive sleep apnea (OSA) that do not tolerate/accept continuous positive airway pressure (CPAP) are candidates for surgical alternatives. Hypoglossal nerve stimulation (HNS) through the implantation of the Inspire (R) device constitutes a minimally invasive operative option. The main objective of this study is to estimate, under real-world clinical practice conditions, the 3-month impact on the quality of life (IQoL) of the HNS in patients with moderate/severe OSA who do not tolerate or accept CPAP, compared to patients who did not receive HNS. As a baseline, the unadjusted EuroQol utility index was 0.764 (SD:0.190) in the intervention group (IGr) and 0.733 (SD:0.205) in the control group (CGr); three months later, the indexes were 0.935 (SD: 0.101) and 0.727 (SD:0.200), respectively. The positive impact on quality of life was estimated to be +0.177 (95% CI: 0.044-0.310; p = 0.010). All dimensions in the IGr improved compared to CGr, especially for usual activities (p < 0.001) and anxiety/depression (p > 0.001). At the end of the follow-up, there was no significant difference in the quality of life between the general Spanish population and the IGr (difference: 0.012; CI95%: -0.03 to -0.057; p = 0.0578) for the same age range; however, there was a difference concerning the CGr (difference: -0.196; CI95%: -0.257 to -0.135; p < 0.001). In conclusion, patients with moderate/severe OSA implanted with the Inspire (R) device showed a positive IQoL. | - |
dc.language.iso | en | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | Área de Medicina Clínica y Epidemiología | - |
dc.subject | Quality of life | - |
dc.subject | Obstructive sleep apnea | - |
dc.subject | Hypoglossal nerve stimulation | - |
dc.subject | Minimally invasive surgical technique | - |
dc.subject | EuroQol-5D-5L | - |
dc.title | Quality of life impact of hypoglossal nerve stimulation with inspire (R) device in patients with obstructive sleep apnea intolerant to continuous positive airway pressure therapy | - |
dc.type | info:eu-repo/semantics/article | - |
dc.relation.publisherversion | https://pubmed.ncbi.nlm.nih.gov/36362892/ | - |
dc.description.note | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). | - |
dc.identifier.doi | 10.3390/life12111737 | - |
dadun.citation.number | 11 | - |
dadun.citation.publicationName | LIFE | - |
dadun.citation.startingPage | 1737 | - |
dadun.citation.volume | 12 | - |
dc.identifier.pmid | 36362892 | - |
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