Reduced folate carrier (RFC) as a predictive marker for response to pemetrexed in advanced non-small cell lung cancer (NSCLC)

Sánchez-Lorenzo, M. L. (María Luisa); Álvarez-Fernández, C. (Carlos); Ruiz-Echeverría, L. (Lucrecia); Rodríguez-Rubi, D. (David); Li-Torres, W. (Walter); Izquierdo-Manuel, M. (Marta); Berros, J. P. (José P.); Luque-Cabal, M. (María); Jiménez-Fonseca, P. (Paula); Villanueva-Palicio, N. (Noemi); Esteban-Gutiérrez, E. (Emilio)

Keywords:

Reduced folate carrier
Pemetrexed
Advanced non-small-cell lung cancer
Predictive marker

Issue Date:

2013

Publisher Version:

https://link.springer.com/article/10.1007/s10637-013-9992-1

Editorial note:

Citation:

Sánchez-Lorenzo, M. L. (María Luisa); Álvarez-Fernández, C. (Carlos); Ruiz-Echeverría, L. (Lucrecia); et al. "Reduced folate carrier (RFC) as a predictive marker for response to pemetrexed in advanced non-small cell lung cancer (NSCLC)". Invest New Drugs. 32, 2013, 377 - 381

Abstract

RFC is the major transport system in mammalian cells for folate cofactors and antifolate therapeutics. The aim of this study was to assess the predictive value of RFC expression in patients receiving pemetrexed for afvanced NSCLC.

URI:

https://hdl.handle.net/10171/68885

Appears in Collections:

DA - CIMA - Tumores sólidos y biomarcadores- Biomarcadores - Artículos de revista

Files in This Item: