Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.creator | Cepeda-Franco, C. (Carmen) | - |
| dc.creator | Mitxelena-Iribarren, O. (Oihane) | - |
| dc.creator | Calero-Castro, F.J.(Francisco José) | - |
| dc.creator | Astigarraga, M.(Malen) | - |
| dc.creator | Castillo-Tuñon, J.M.(Juan Manuel) | - |
| dc.creator | Laga, I. (Iman) | - |
| dc.creator | Pereira, S. (Sheila) | - |
| dc.creator | Arana-Alonso, S. (Sergio) | - |
| dc.creator | Mujika-Garmendia, M. (Maite) | - |
| dc.creator | Padillo-Ruiz, J. (Javier) | - |
| dc.date.accessioned | 2024-02-08T09:13:56Z | - |
| dc.date.available | 2024-02-08T09:13:56Z | - |
| dc.date.issued | 2023-02 | - |
| dc.identifier.citation | Cepeda-Franco, C., Mitxelena-Iribarren, O., Calero-Castro, F. J., Astigarraga, M., Castillo-Tuñon, J. M., Laga, I., ... & Padillo-Ruiz, J. (2023). TARTESSUS: A Customized Electrospun Drug Delivery System Loaded with Irinotecan for Local and Sustained Chemotherapy Release in Pancreatic Cancer. Bioengineering, 10(2), 183. | es_ES |
| dc.identifier.issn | 2306-5354 | - |
| dc.identifier.uri | https://hdl.handle.net/10171/68901 | - |
| dc.description.abstract | Post-surgical chemotherapy in pancreatic cancer has notorious side effects due to the high dose required. Multiple devices have been designed to tackle this aspect and achieve a delayed drug release. This study aimed to explore the controlled and sustained local delivery of a reduced drug dose from an irinotecan-loaded electrospun nanofiber membrane (named TARTESSUS) that can be placed on the patients' tissue after tumor resection surgery. The drug delivery system formulation was made of polycaprolactone (PCL)... | es_ES |
| dc.description.sponsorship | This research was partially funded by the Carlos III Health Institute (Fondos de Investigación Sanitarias) under the contract PI19/01821. Fundación Novia Salcedo provided the funding needed for the contract of Malen Astigarraga. | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | MDPI | es_ES |
| dc.rights | info:eu-repo/semantics/openAccess | es_ES |
| dc.subject | Electrospinning. | es_ES |
| dc.subject | Nanofiber membrane. | es_ES |
| dc.subject | Pancreatic cancer. | es_ES |
| dc.subject | Drug delivery system. | es_ES |
| dc.subject | Irinotecan. | es_ES |
| dc.title | TARTESSUS: A Customized Electrospun Drug Delivery System Loaded with Irinotecan for Local and Sustained Chemotherapy Release in Pancreatic Cancer | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.editorial.note | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. | es_ES |
| dc.identifier.doi | 10.3390/bioengineering10020183 | - |
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