Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Ochoa, M.C. (María Carmen) | - |
dc.creator | Moreno-Aliaga, M. J. (María Jesús) | - |
dc.creator | Martinez-Gonzalez, M.A. (Miguel Ángel) | - |
dc.creator | Martinez, J.A. (José Alfredo) | - |
dc.creator | Marti-del-Moral, A. (Amelia) | - |
dc.creator | Grupo de Estudio Navarro de la Obesidad Infantil (GENOI) | - |
dc.date.accessioned | 2012-04-21T17:47:11Z | - |
dc.date.available | 2012-04-21T17:47:11Z | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Ochoa MC, Moreno-Aliaga MJ, Martinez-Gonzalez MA, Martinez JA, Marti A, GENOI Members. TV watching modifies obesity risk linked to the 27Glu polymorphism of the ADRB2 gene in girls. Int J Pediatr Obes. 2006;1(2):83-8 | es_ES |
dc.identifier.issn | 1747-7166 | - |
dc.identifier.uri | https://hdl.handle.net/10171/21711 | - |
dc.description.abstract | OBJECTIVE: A matched case-control study was conducted in a population of Spanish children and adolescents (5-18 years old), to assess the interaction between the Gln27Glu polymorphism of the ADRB2 and television (TV) watching on obesity risk. PATIENTS: Obese (n=165) and control subjects (n=165) matched by sex and age were recruited and classified according to Spanish reference data. Results. Using conditional logistic regression, we calculated the obesity risk linked to the polymorphism. A statistically significant association was found for 27Glu carrier allele girls (OR = 1.95; 95% CI = 1.02-3.70), but no association was apparent among boys. In the fully adjusted model, the odds ratio for obesity linked to the genotype Glu27Glu in the female population rose to 4.84 (95% CI = 1.37-17.10). Moreover, we found a significant negative interaction between hours of TV watching and the Gln27Glu polymorphism for obesity risk in girls. Surprisingly, among 27Glu carrier subjects, even girls with a low level of TV watching ( < 12.5 h/week) had a high obesity risk (OR = 4.60; 95% CI = 1.01-20.02), which was not very different to the odds ratio values for sedentary girls carrying the 27 Glu allele watching TV more than 12.5 h/week (OR = 6.05; 95% CI = 1.31-27.71). Conclusion. A higher risk of obesity was found for girls carrying the 27Glu allele of the ADRB2 gene even when they spent less than 12.5 h/week watchin | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Informa Healthcare | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | ADRB2 | es_ES |
dc.subject | Gln27Glu polymorphism | es_ES |
dc.subject | Obesity risk | es_ES |
dc.subject | Television | es_ES |
dc.subject | Children | es_ES |
dc.title | TV watching modifies obesity risk linked to the 27Glu polymorphism of the ADRB2 gene in girls | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | http://dx.doi.org/10.1080/17477160600650386 | es_ES |
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