Full metadata record
DC Field | Value | Language |
---|---|---|
dc.creator | Paramo, J.A. (José Antonio) | - |
dc.creator | Orbe, J. (Josune) | - |
dc.creator | Rodriguez, J.A. (José Antonio) | - |
dc.date.accessioned | 2012-07-06T09:01:10Z | - |
dc.date.available | 2012-07-06T09:01:10Z | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | Paramo JA, Orbe J, Rodriguez JA. Estabilización de la placa de ateroma: un nuevo concepto basado en la biología dinámica de la aterosclerosis. Med Clin (Barc) 2003 Nov 1;121(15):583-587. | es_ES |
dc.identifier.issn | 0025-7753 | - |
dc.identifier.uri | https://hdl.handle.net/10171/22851 | - |
dc.description.abstract | As it is well-known, a thrombus evolving into a disrupted/eroded atherosclerotic plaque causes most acute coronary syndromes. Plaque stabilization via reduction of the lipid core and/or thickening of the fibrous cap is one of the possible mechanisms accounted for the clinical benefits displayed by different anti-atherosclerotic strategies. The concept of plaque stabilization was developed to explain how lipid-lowering agents could decrease adverse coronary events without substantial modifications of the atherosclerotic lesion. A number of imaging modalities (vascular ultrasound, MRI, and coronary computed tomography) are used for non-invasive assessment of atherosclerosis; most of them can identify luminal stenosis, wall thickness and plaque volume and composition, and can even characterize the rupture-prone vulnerable plaques. Several classes of drugs, including statins, ACE inhibitors, -blockers, and antithrombotics, are able to reduce the plaque burden and the incidence of cardiovascular events; this may be attibutable, at least in part, to plaque-stabilizing effects and the improvement of endothelial dysfunction | es_ES |
dc.language.iso | spa | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Aterosclerosis | es_ES |
dc.subject | Estabilización de la placa | es_ES |
dc.subject | Técnicas no invasivas de imagen vascular | es_ES |
dc.subject | Estrategias antiateroscleróticas | es_ES |
dc.title | Estabilización de la placa de ateroma: un nuevo concepto basado en la biología dinámica de la aterosclerosis | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | http://www.elsevier.es/en/linksolver/ft/ivp/0025-7753/121/583 | es_ES |
dc.type.driver | info:eu-repo/semantics/article | es_ES |
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